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Comparative effectiveness research: Challenges for medical journals

Harold C Sox1, Mark Helfand2*, Jeremy Grimshaw3, Kay Dickersin4, The PLoS Medicine Editors5, David Tovey5, J André Knottnerus6 and Peter Tugwell7

Author Affiliations

1 Dartmouth Institute, Dartmouth Medical School, Hanover, New Hampshire, USA

2 Portland VA Medical Center and Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA

3 Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

4 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

5 The Cochrane Library, London, UK

6 Department of General Practice, University of Maastricht, Maastricht, The Netherlands

7 Departments of Medicine, and Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada

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Trials 2010, 11:45  doi:10.1186/1745-6215-11-45

Published: 28 April 2010


Editors from a number of medical journals lay out principles for journals considering publication of Comparative Effectiveness Research (CER). In order to encourage dissemination of this editorial, this article is freely available in PLoS Medicine and will be also published in Medical Decision Making, Croatian Medical Journal, The Cochrane Library, Trials, The American Journal of Managed Care, and Journal of Clinical Epidemiology.