Table 6

Safety results that provide a posterior probability of 90% or more of observing a percentage of serious adverse events in the overall sample higher than an acceptable maximum (4%)
Number of serious adverse events Number of cumulative patients in study
2 13 to 27
3 28 to 44
4 45 to 61
5 62 to 79
6 80 to 98
7 99 to 117
8 118 to 137
9 138 to 157
10 158 to 177
11 178 to 198
12 199 to 218
13 219 to 239
14 240 to 260
15 261 to 281
16 282 to 302
17 303 to 323
18 324 to 345
19 346 to 366
20 367 to 388
21 389 to 410
22 411 to 431
23 432 to 453
24 454 to 475
25 476 to 497
26 498 to 519
27 520 to 541
28 542 to 563
29 564 to 585
30 586 to 608
31 609 to 630
32 631 to 652
33 653 to 674
34 675 to 679

Zamboni et al.

Zamboni et al. Trials 2012 13:183   doi:10.1186/1745-6215-13-183

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