|
Patient Demographics |
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| PREPARE Patients (N = 700) |
MIRACLE ICD Patients (N = 415) |
EMPIRIC Patients (N = 276) |
Combined Control (MIRACLE ICD and EMPIRIC) Patients (N = 691) |
|
|
|
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| Gender (N, %) |
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| Male |
555 (79.3%) |
310 (74.7%) |
222 (80.4%) |
532 (77%) |
| Female |
145 (20.7%) |
105 (25.3%) |
54 (19.6%) |
159 (23%) |
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| Age (years) |
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| Mean ± Standard Deviation |
67.4 ± 12.2 |
65.4 ± 11.5 |
65.6 ± 12 |
65.5 ± 11.7 |
| Median |
68.7 |
67.9 |
67.3 |
67.7 |
| Minimum – Maximum |
19.2 – 92.2 |
31 – 89 |
23.3 – 91.4 |
23.3 – 91.4 |
| n (%) |
700 (100%) |
415 (100%) |
276 (100%) |
691 (100%) |
|
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| Baseline Left Ventricular Ejection Fraction (%) |
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| Mean ± Standard Deviation |
27.7 ± 10.5 |
21 ± 6.8 |
30.3 ± 11 |
24.7 ± 9.8 |
| Median |
25 |
20 |
30 |
25 |
| Minimum – Maximum |
5 – 80 |
6 – 35 |
5 – 70 |
5 – 70 |
| n (%) |
691 (98.7%) |
413 (99.5%) |
273 (98.9%) |
686 (99.3%) |
|
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| Baseline New York Heart Association Classification (N, %) |
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| Class I |
117 (16.7%) |
0 (0%) |
36 (13%) |
36 (5.2%) |
| Class II |
297 (42.4%) |
137 (33%) |
102 (37%) |
239 (34.6%) |
| Class III |
268 (38.3%) |
237 (57.1%) |
36 (13%) |
273 (39.5%) |
| Class IV |
18 (2.6%) |
41 (9.9%) |
3 (1.1%) |
44 (6.4%) |
| Not Collected* |
0 (0%) |
0 (0%) |
99 (35.9%) |
99 (14.3%) |
|
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| Ischemic Cardiomyopathy |
488 (69.7%) |
238 (57.5%) |
155 (56.2%) |
393 (57.0%) |
|
|
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| Myocardial Infarction (N, %) |
421 (60.1%) |
193 (46.6%) |
192 (69.6%) |
385 (55.8%) |
|
N/A = not collected *NYHA Class was only collected in the EMPIRIC Trial for patients with documented heart failure | ||||
Wilkoff et al. Trials 2006 7:18 doi:10.1186/1745-6215-7-18 |
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