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This is the Trials news archive.

Old news items may link to websites that are no longer available.

Trials News for the last 365 days

Quantifying data quality for clinical trials using electronic data capture (PLoS One)

(Date posted: 4 September 2008)

Systematic review of the empirical evidence of study publication bias and outcome reporting bias (PLoS One)

(Date posted: 4 September 2008)

Research ethics committees identify and correct problems in applications to do cancer trials, UK

(Date posted: 1 September 2008)

Children are not just small adults: the urgent need for high-quality trial evidence in children

(Date posted: 27 August 2008)

Guest authorship, mortality reporting, and integrity in rofecoxib studies (JAMA)

(Date posted: 27 August 2008)

Trialists should describe how they deal with missing data

(Date posted: 13 August 2008)

Researchers see a need for speed in EU trial approvals

(Date posted: 7 August 2008)

Prof Desmond Julian spoke to Dr Eugene Braunwald at this year’s ESC congress

(Date posted: 28 July 2008)

Next stop, don't block the doors: opening up access to clinical trials results

(Date posted: 23 July 2008)

Confronting therapeutic ignorance (BMJ)

(Date posted: 21 July 2008)

Patient consent for information sharing not always possible or appropriate (BMJ)

(Date posted: 21 July 2008)

Enhancing the quality and transparency of health research (BMJ)

(Date posted: 10 July 2008)

What is missing from descriptions of treatment in trials and reviews? (BMJ)

(Date posted: 27 June 2008)

Number of UK patients offered participation in clinical trials will be boosted (BMJ)

(Date posted: 27 June 2008)

Guidelines for reporting health research: The EQUATOR Network's survey of guideline authors (PLoS Medicine)

(Date posted: 25 June 2008)

EQUATOR: reporting guidelines for health research

(Date posted: 25 June 2008)

RA patient priorities and motivators for clinical trial involvement

(Date posted: 17 June 2008)

Helping editors, peer reviewers, and authors improve the clarity, completeness, and transparency of reporting health research

(Date posted: 16 June 2008)

Organisers of cancer clinical trials are neglecting teenagers and young adults

(Date posted: 10 June 2008)

Clinical trials in Africa receive funding boost

(Date posted: 9 June 2008)

Why are clinicians not embracing the results from pivotal clinical trials in severe sepsis? (PLoS ONE)

(Date posted: 6 June 2008)

Determining what outcomes are important in diabetes trials

(Date posted: 4 June 2008)

Stopping clinical trials early (BMJ)

(Date posted: 30 May 2008)

New book demystifies the world of clinical trials

(Date posted: 29 May 2008)

How to interpret figures in reports of clinical trials (BMJ)

(Date posted: 27 May 2008)

Trials on trial (Nature)

(Date posted: 23 May 2008)

Assessing patients’ improvement in clinical trials (BMJ)

(Date posted: 23 May 2008)

The future of clinical trials evaluating blood substitutes (JAMA)

(Date posted: 21 May 2008)

Happy International Clinical Trials Day!

(Date posted: 20 May 2008)

Electronic sharing of patients’ data requires their explicit consent, report says (BMJ)

(Date posted: 20 May 2008)

Trastuzumab: possible publication bias (The Lancet)

(Date posted: 20 May 2008)

Standardising outcomes in paediatric clinical trials

(Date posted: 2 May 2008)

Measurements poor for assessing clinical trials with children

(Date posted: 30 April 2008)

The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias

(Date posted: 29 April 2008)

Blood substitutes raise risk of heart death- study

(Date posted: 29 April 2008)

FDA proposal on drug articles under fire

(Date posted: 22 April 2008)

Impugning the integrity of medical science (JAMA)

(Date posted: 17 April 2008)

Drug firm accused of death rate data failures

(Date posted: 16 April 2008)

When should data and safety monitoring committees share interim results in cardiovascular trials? (JAMA)

(Date posted: 10 April 2008)

EQUATOR: reporting guidelines for health research (The Lancet)

(Date posted: 10 April 2008)

Pharma firms end drug trials early in rush to beat rivals, say experts

(Date posted: 9 April 2008)

Trial participants need to be more representative of patients (BMJ)

(Date posted: 8 April 2008)

India overtakes China as No.1 destination for clinical trials

(Date posted: 7 April 2008)

Report claims clinical trials miss many populations

(Date posted: 4 April 2008)

Vietnam starts human trials for bird flu vaccine

(Date posted: 3 April 2008)

Drugs companies Merck and Schering-Plough ‘suppressed Ezetrol trial results’

(Date posted: 31 March 2008)

Independant safety monitoring 'lacking' in child trials

(Date posted: 28 March 2008)

Hospitals that participate in clinical trials may provide better patient care

(Date posted: 27 March 2008)

Could an open-source clinical trial data-management system be what we have all been looking for? (PLoS Medicine)

(Date posted: 26 March 2008)

Moving toward transparency of clinical trials (Science)

(Date posted: 14 March 2008)

British government to demand clinical trial data

(Date posted: 13 March 2008)

Publicly funded drug trials will counteract the corruption and inefficiency of testing

(Date posted: 12 March 2008)

Firm attacked over drug trial data

(Date posted: 11 March 2008)

HIV prevention trials 'hindered by obstacles'

(Date posted: 6 March 2008)

Forcing drug companies to publish negative trial results ‘is against law’

(Date posted: 27 February 2008)

Western clinical trials bad for traditional medicine: South African minister

(Date posted: 26 February 2008)

Registration open for the EQUATOR Network launch meeting

(Date posted: 21 February 2008)

Stem cell therapy trials to mend shattered bones coming soon

(Date posted: 19 February 2008)

Facebook for Trials?

(Date posted: 14 February 2008)

Cancer data? sorry, can’t have it

(Date posted: 1 February 2008)

When drug trials go wrong, patients have little recourse

(Date posted: 1 February 2008)

Suicide warning over clinical trials

(Date posted: 31 January 2008)

Drug firms 'bury' poor trial results

(Date posted: 22 January 2008)

Study probes why US blacks wary of medical trials

(Date posted: 16 January 2008)

Study into informed consent for clinical trials

(Date posted: 14 January 2008)

It’s time to reappraise recruitment of South Asians to clinical trials (BMJ)

(Date posted: 10 January 2008)

Non-drug industry funded research (BMJ)

(Date posted: 10 January 2008)

Clinical data initiates long-term safety study for Vilazodone

(Date posted: 19 December 2007)

The Judge group delivers application solutions to aid cancer patients in finding clinical trials

(Date posted: 6 December 2007)

Stroke study to add patients who cannot give immediate consent

(Date posted: 3 December 2007)

Arthritis gene therapy trial resumes after patient death investigated

(Date posted: 28 November 2007)

Early clinical trials lack diversity

(Date posted: 21 November 2007)

Lilly sets new prasugrel trial after mixed results

(Date posted: 6 November 2007)

Participants left uninformed in some halted medical trials

(Date posted: 31 October 2007)

Long-term data from a landmark phase III trial show survival benefit at three- and four-years in patients with glioblastoma multiforme

(Date posted: 31 October 2007)

Dendreon completes target enrollment of 500 patients in phase 3 IMPACT study of Provenge(R) for advanced prostate cancer

(Date posted: 24 October 2007)

Pharmion initiates pivotal phase 3 study of Amrubicin in small cell lung cancer

(Date posted: 18 October 2007)

Open clinical trials

(Date posted: 16 October 2007)

DeCODE launches phase II clinical testing of DG051 for the prevention of heart attack

(Date posted: 10 October 2007)

Horizon therapeutics initiates long-term phase 3 safety study for lead product candidate HZT-501

(Date posted: 9 October 2007)

Anthera announces completion of enrollment and dosing in phase II trial of A-002 for the treatment of cardiovascular disease

(Date posted: 4 October 2007)

ADVENTRX Pharmaceuticals announces results from phase 2b clinical trial of ANX-510 (CoFactor(R))

(Date posted: 3 October 2007)

Nastech Pharmaceutical company announces initiation of phase 2 clinical trial for PYY3 36 nasal spray to treat obesity

(Date posted: 2 October 2007)

Annual flu shots may be of little benefit to the elderly (register with Medscape to view)

(Date posted: 28 September 2007)

RE-NOVATE published: dabigatran promising in VTE prevention (register with Medscape to view)

(Date posted: 25 September 2007)

Breast-feeding may not reduce risk for asthma or allergy (register with Medscape to view)

(Date posted: 25 September 2007)

Aerobic and resistance training improve glycemic control in type 2 diabetes (register with Medscape to view)

(Date posted: 19 September 2007)

CPAP therapy may reduce up-transfers for newborns with respiratory distress (register with Medscape to view)

(Date posted: 19 September 2007)

Sinovac commences vaccination on volunteers for phase II clinical trial on pandemic influenza H5N1 vaccine

(Date posted: 12 September 2007)

Symptom benefits, but no life savings with noninvasive ventilation for acute cardiogenic pulmonary edema (register with Medscape to view)

(Date posted: 11 September 2007)

Atrial Fibrillation reduced with minimal ventricular pacing: SAVE-PACE published (register with Medscape to view)

(Date posted: 11 September 2007)

OASIS-5 substudy: women fare worse with invasive strategy (register with Medscape to view)

(Date posted: 11 September 2007)

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