Trials

Trials is an open access, peer-reviewed, online journal that encompasses all aspects of the performance and findings of randomized controlled trials. We publish articles on general trial methodology as well as protocols, commentaries and traditional results papers - regardless of outcome or significance of findings.

Editors-in-Chief

Doug Altman, University of Oxford
Curt Furberg, Wake Forest University of Medicine
Jeremy Grimshaw, Ottawa Health Research Institute
Peter Rothwell, University of Oxford

Editorial Board | Instructions for authors | FAQ

Articles

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Study protocol

A multi-site single blind clinical study to compare the effects of prolonged exposure, eye movement desensitization and reprocessing and waiting list on patients with a current diagnosis of psychosis and co morbid post traumatic stress disorder: study protocol for the randomized controlled trial Treating Trauma in Psychosis

de Bont PAJM, van den Berg DPG, van der Vleugel BM, de Roos C, Mulder CL, Becker ES, de Jongh A, van der Gaag M et al. Trials 2013, 14:151 (23 May 2013)
Study protocol

Transfusion requirements in septic shock (TRISS) trial - comparing the effects and safety of liberal versus restrictive red blood cell transfusion in septic shock patients in the ICU: protocol for a randomised controlled trial

Holst LB, Haase N, Wetterslev J, Wernerman J, Åneman A, Guttormsen AB, Johansson PI, Karlsson S et al. Trials 2013, 14:150 (23 May 2013)
Study protocol

Comparative effectiveness of a complex Ayurvedic treatment and conventional standard care in osteoarthritis of the knee -- study protocol for a randomized controlled trial

Witt CM, Michalsen A, Roll S, Morandi A, Gupta S, Rosenberg M, Kronpaß L, Stapelfeldt E et al. Trials 2013, 14:149 (23 May 2013)
Study protocol

A pharmacist-led system-change smoking cessation intervention for smokers admitted to Australian public hospitals (GIVE UP FOR GOOD): study protocol for a randomised controlled trial

Thomas D, Abramson MJ, Bonevski B, Taylor S, Poole S, Weeks GR, Dooley MJ and George J Trials 2013, 14:148 (21 May 2013)
Study protocol

An open-label study of effects of acupuncture on chronic fatigue syndrome and idiopathic chronic fatigue: study protocol for a randomized controlled trial

Kim JE, Hong KE, Kim HJ, Choi JB, Baek YH, Seo BK, Lee S, Kang KW et al. Trials 2013, 14:147 (21 May 2013)
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Latest from the ISRCTN Register

24 May 2013: ISRCTN51981241 - Supervision preference for an effective walking program among older individuals with osteoarthritis of the knee

24 May 2013: ISRCTN42686094 - RESCUE ESES: a Randomized European trial of Steroids versus Clobazam Usage for Encephalopathy with Electrical Status Epilepticus in Sleep

24 May 2013: ISRCTN93873801 - Effect of occupational therapy in elderly people living at home

24 May 2013: ISRCTN63407050 - CORAL: Cancer of the OvaRy Abiraterone triaL

23 May 2013: ISRCTN47136464 - Efficacy of different schemes of supplementation with micronutrient powder for the control of anemia and micronutrient deficiency in children

Meetings and Events

You may be interested in one of these upcoming events:

ACRP's 2013 Global Conference & Exhibition 13th - 16th April, Orlando, Florida
SCT 34th Annual Meeting May 19th - 22nd Boston, Massachusetts
2nd Annual Cancer Immunotherapy Conference April 4-5, Washington, DC

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Comments

Response to comment by Hamilton et al.

Comment on: Lundh et al. Trials 2012, 13:146
Addressing the implication made by the authors that if...

Comment on: Lundh et al. Trials 2012, 13:146
Efficacy due to alcohol or something else in the mouthwash...

Comment on: Marchetti et al. Trials 2012, 12:262

AllTrials campaign

Trials supports the AllTrials initiative, campaigning for the registration of all trials past and present, and the reporting of full methods and the results of all trials.

Editor's profile

Curt D. Furberg

Professor Curt D. Furberg is a co-Editor-in-Chief of Trials. He is a Professor of Public Health at Wake Forest University Health Sciences, where he has been since 1986. Professor Furberg earned his MD in Sweden in 1963 and has worked at the Minneapolis LRC Clinic as the Chief of the Clinical Trials Branch and the Clinical Trials Research Branch of the National Heart, Lung, and Blood Institute - where he was the Associate Director for the Clinical Applications and Prevention Program. In addition, Professor Furberg is a nationally and internationally recognized expert on the design, conduct, analysis and monitoring of clinical trials. He has worked closely with investigators at the NIH and several pharmaceutical companies and is also a world-renowned cardiovascular epidemiologist with special expertise in lipid-lowering and blood pressure-lowering therapies. He is a strong proponent for evidence-based medicine, and his public health background provides a strong foundation for his views on drug evaluation and patient safety.

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