Email updates

Keep up to date with the latest news and content from Trials and BioMed Central.

Open Access Study protocol

Effectiveness of phototherapy incorporated into an exercise program for osteoarthritis of the knee: study protocol for a randomized controlled trial

Carly de Coelho, Ernesto Cesar Leal-Junior, Daniela Aparecida Biasotto-Gonzalez, André Serra Bley, Paulo de Carvalho, Fabiano Politti, Tabajara de Gonzalez, Adriano Rodrigues de Oliveira, Marcelo Frigero, Marilia Barbosa Garcia, Almir Vieira Dibai-Filho and Cid André Gomes

Author Affiliations

For all author emails, please log on.

Trials 2014, 15:221  doi:10.1186/1745-6215-15-221

Published: 11 June 2014

Abstract (provisional)


Osteoarthritis is a chronic disease with a multifactor etiology involving changes in bone alignment, cartilage, and other structures necessary to joint stability. There is a need to investigate therapeutic resources that combine different wavelengths as well as different light sources (low-level laser therapy and light-emitting diode therapy) in the same apparatus for the treatment of osteoarthritis. The aim of the proposed study is to analyze the effect of the incorporation of phototherapy into a therapeutic exercise program for individuals with osteoarthritis of the knee.


A double-blind, controlled, randomized clinical trial will be conducted involving patients with osteoarthritis of the knee. Evaluations will be performed using functional questionnaires before and after the treatment protocols, in a reserved room with only the evaluator and participant present, and no time constraints placed on the answers or evaluations. The following functional tests will also be performed: stabilometry (balance assessment), dynamometry (muscle strength of gluteus medius and quadriceps), algometry (pain threshold), fleximeter (range of motion), timed up-and-go test (functional mobility), and the functional reach test. The participants will then be allocated to three groups through a randomization process using opaque envelopes: exercise program, exercise program + phototherapy, or exercise program + placebo phototherapy, all of which will last for eight weeks.


The purpose of this randomized clinical trial is to analyze the effect of the incorporation of phototherapy into a therapeutic exercise program for osteoarthritis of the knee. The study will support the practice based on evidence to the use of phototherapy in individuals with a diagnosis of osteoarthritis of the knee. Data will be published after the study is completed.

Trial registration: The protocol for this study has been submitted to Clinical Trials, registration number NCT02102347, on 29 March 2014.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.