Table 1

Relationship between criteria for defining a "high-risk" sub-group and whether a patient has an event during a clinical trial.



Event?





Yes
No

Meet criteria for "high-risk"?
Yes
396
624

No
632
3,799

Hypothetical data are given for the purposes of illustration.

Sensitivity = 396 ÷ (396+632) = 39%

Specificity = 3799 ÷ (624+3799) = 86%

Vickers et al. Trials 2006 7:30   doi:10.1186/1745-6215-7-30